Clinical performance

Craig GG, Knight GM, McIntyre JM; Clinical evaluation of diamine silver fluoride/potassium iodide as a dentine desensitizing agent. A pilot study. Australian Dental Journal 2012; 57:308-311.

The aim of this study was to compare the effficacy of an experimental diamine silver fluoride/potassium iodide product with an oxalic acid-based preparation in reducing dentine hypersensitivity. The study was conducted as a double-blind, randomized clincial trial. A total of 19 subjects with dentine hypersensitivity on both sides of their upper arch were selected. The most sensitive tooth in each quadrant was identified and received a cold stimulus. The response was recorded on a visual anaologue scale (VAS). The tooth thus selected was treated with one treatment agents. One week later the level of dentine sensitivity was assessed. Participants were also asked for their subjective assessment of treatment effects.
Conclusion: It was concluded that an experimental diamine silver fluoride/potassium iodide product has potential as a treatment for dentine hypersensitivity.

Invitro performance

Willershausen I et al ; Penetration Potential of a Silver Diamine Fluoride Solution on Dentin Surfaces. An Ex Vivo Study;

The aim of this study was to assess the effect of a silver diamine fluoride solution on human dentin samples.
Conclusion: In this invitro study, the effect of silver diamine fluoride on dentin surfaces could be demonstarted. These findings can explain a certain desensitizing effect, but a direct translation to invivo conditions can only be done with caution.

Invitro performance

Bersezio C et al ; Dentine hydrolylic conductance with different application times of diamine silver fluoride/potassium iodide desensitizing solution;

The aim of this study was to evaluate the influence of time of application of diamine silver fluoride (Riva Star) on the hydrodaulic conductance.
Conclusion: There was no difference in hydraulic conductance between disks with different application times of desensitizing solutions of diamine silve/potassium iodide.